The use of haemodialysis for the treatment of phenobarbitone intoxication 30 hours after ingestion

Abstract An 18‐month‐old male neutered Cocker Spaniel presented with a comatose mentation to its primary care veterinarian following the presumed ingestion of 216 mg/kg phenobarbitone 2 hours prior. Following failure improve intravenous fluids, lipid emulsion therapy, and supportive care, patient was then referred tertiary referral centre for further treatment 30 ingestion. Mechanical ventilation initiated due severe hypoventilation (PvCO : 69.9 mmHg) before underwent 300‐minute prolonged veno‐venous haemodiafiltration cycle performed using continuous haemodialysis‐based platform high‐flux dialyser. The demonstrated rapid neurological improvement being extubated after 4 hours, becoming responsive ambulatory 5 from initiation treatment. discharged 60 completion haemodialysis. This is first report in veterinary literature effective use treat intoxication